IR 700DX

IR 700DX (IR 700DX NHS ester) is a near-infrared (NIR) phthalocyanine dye with extremely high photostability and fluorescence intensity. IR 700DX binds to biomolecules. IR 700DX has excellent water solubility, large extinction coefficient, high fluorescence quantum yield, and does not aggregate in high ionic strength buffers. IR 700DX can be used as a highly flexible photosensitizer[1][2][3].

Product Specifications

CAS Number

[916821-46-0]

Product Name Alternative

IR 700DX NHS ester

UNSPSC

12171500

Target

Fluorescent Dye

Type

Dye Reagents

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/irdye-700dx.html

Purity

94.23

Solubility

10 mM in DMSO

Smiles

C[Si](CCC[N+](CCC[S](=O)(O[Na])=O)(CCC[S](=O)(O[Na])=O)CCC[S](=O)([O-])=O)(C)[O-][Si+4]12([N-]3C4=NC(C5=CC=CC=C65)=[N]1C6=NC7=C(C=CC=C8)C8=C9[N-]27)([N](C%10=N9)=C(C%11=CC=CC=C%10%11)N=C3C%12=CC=CC(OCCCOC(NCCCCCC(ON(C%13=O)C(CC%13)=O)=O)=O)=C4%12)[O-][Si](C)(C)CCC[N+](CCC[S](=O)(O[Na])=O)(CCC[S](=O)(O[Na])=O)CCC[S](=O)([O-])=O

Molecular Formula

C74H96N12Na4O27S6Si3

Molecular Weight

1954.22

References & Citations

[1]Mitsunaga M, et al. Cancer cell-selective in vivo near infrared photoimmunotherapy targeting specific membrane molecules. Nat Med. 2011 Nov 6;17 (12) :1685-91.|[2]Peng X, et al. Phthalocyanine dye as an extremely photostable and highly fluorescent near-infrared labeling reagent[C]//Optical Molecular Probes for Biomedical Applications. SPIE, 2006, 6097: 113-124. |[3]Tynan CJ, et al. Multicolour single molecule imaging in cells with near infra-red dyes. PLoS One. 2012;7 (4) :e36265.