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Recombinant Rat Cardiotrophin-1 protein (Ctf1) (Active)

Product Specifications

Background

Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST, gp130 receptor.

Product Name Alternative

CT-1

Gene ID

29201

UniProt

Q63086

Target

MSQREGSLED HQTDSSFSFL PHLEAKIRQT HNLARLLTKY ADQLLEEYVQ QQGEPFGLPG FSPPRLPLAG LSGPAPSHAG LPVSERLRQD AAALSALPAL LDAVRRRQAE LNPRAPRLLR SLEDAARQVR ALGAAVETVL AALGAAARGP VPEPVATSAL FTSNSAAGVF SAKVLGLHVC GLYGEWVSRT EGDLGQLVPG GVA

Purification

>95% as determined by SDS-PAGE and HPLC.

Bioactivity

Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 0.5 ng, ml, corresponding to a specific activity of 2.0 106 IU, mg.

Storage Conditions

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.

Calculated Molecular Weight

21.4 kDa

Formulation

0.2 ?m filtered 20 mM PB, pH 7.4, 150mM NaCl , lyophilized

Host or Source

E.Coli

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