11 (Z),14 (Z) -Eicosadienoic acid
Selected Variant
HY-149589-01
Size: 25 mg
11 (Z),14 (Z) -Eicosadienoic acid is a unsaturated fattly acid that inhibits [3H] leukotriene B4 (LTB4) binding to pig neutrophil membranes with a Ki of 3 μM. 11 (Z),14 (Z) -Eicosadienoic acid has inflammatory activities[1][2].
Product Specifications
CAS Number
5598-38-9
UNSPSC
12352211
Hazard Statement
H315, H319
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/11-z-14-z-eicosadienoic-acid.html
Purity
98.0
Solubility
DMSO : 125 mg/mL (ultrasonic) |Ethanol : ≥ 100 mg/mL
Smiles
CCCCC/C=C\C/C=C\CCCCCCCCCC(O)=O
Molecular Formula
C20H36O2
Molecular Weight
308.50
Precautions
H315, H319
References & Citations
[1]Carballeira NM, et al. Identification of naturally occurring trans, trans delta 5,9 fatty acids from the sponge Plakortis halichondroides. Lipids. 1990 Dec;25 (12) :835-40. |[2]Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52 (5) :293-7.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Price
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