11 (Z),14 (Z) -Eicosadienoic acid

11 (Z),14 (Z) -Eicosadienoic acid is a unsaturated fattly acid that inhibits [3H] leukotriene B4 (LTB4) binding to pig neutrophil membranes with a Ki of 3 μM. 11 (Z),14 (Z) -Eicosadienoic acid has inflammatory activities[1][2].

Product Specifications

CAS Number

[5598-38-9]

UNSPSC

12352211

Hazard Statement

H315, H319

Target

Leukotriene Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/11-z-14-z-eicosadienoic-acid.html

Purity

98.0

Solubility

DMSO : 125 mg/mL (ultrasonic) |Ethanol : ≥ 100 mg/mL

Smiles

CCCCC/C=C\C/C=C\CCCCCCCCCC(O)=O

Molecular Formula

C20H36O2

Molecular Weight

308.50

Precautions

H315, H319

References & Citations

[1]Carballeira NM, et al. Identification of naturally occurring trans, trans delta 5,9 fatty acids from the sponge Plakortis halichondroides. Lipids. 1990 Dec;25 (12) :835-40. |[2]Yagaloff KA, et al. Essential fatty acids are antagonists of the leukotriene B4 receptor. Prostaglandins Leukot Essent Fatty Acids. 1995 May;52 (5) :293-7.