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FAUC-312

FAUC-312, a tetrahydropyrimidine, is a strong and highly selective dopamine D4 receptor partial agonist (Ki=1.5 nM) [1].

Product Specifications

CAS Number

562104-72-7

UNSPSC

12352005

Target

Dopamine Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/fauc-312.html

Smiles

C1(C2=CC=CC=C2)=NCC[C@H](N1)CN3CCN(CC3)C4=CC=CC=C4

Molecular Formula

C21H26N4

Molecular Weight

334.46

References & Citations

[1]Jürgen Einsiedel, et al. Cyclic amidines as benzamide bioisosteres: EPC synthesis and SAR studies leading to the selective dopamine D4 receptor agonist FAUC 312. Bioorg Med Chem Lett. 2003 Mar 10;13 (5) :851-4.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

D1 Receptor; D2 Receptor; D3 Receptor; D4 Receptor

Frequently Asked Questions

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