FAUC-312
FAUC-312, a tetrahydropyrimidine, is a strong and highly selective dopamine D4 receptor partial agonist (Ki=1.5 nM) [1].
Product Specifications
CAS Number
562104-72-7
UNSPSC
12352005
Target
Dopamine Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fauc-312.html
Smiles
C1(C2=CC=CC=C2)=NCC[C@H](N1)CN3CCN(CC3)C4=CC=CC=C4
Molecular Formula
C21H26N4
Molecular Weight
334.46
References & Citations
[1]Jürgen Einsiedel, et al. Cyclic amidines as benzamide bioisosteres: EPC synthesis and SAR studies leading to the selective dopamine D4 receptor agonist FAUC 312. Bioorg Med Chem Lett. 2003 Mar 10;13 (5) :851-4.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
D1 Receptor; D2 Receptor; D3 Receptor; D4 Receptor
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