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Cedrin

Cedrin is a natural flavonoid that can be found in Cedrus deodara. Cedrin protects PC12 cells against neurotoxicity induced by Aβ1-42. Cedrin can reduce reactive oxygen species overproduction, increase the activity of superoxide dismutase and decrease malondialdehyde content[1].

Product Specifications

CAS Number

[75513-81-4]

UNSPSC

12352005

Hazard Statement

H315-H319-H341

Target

Reactive Oxygen Species (ROS)

Type

Natural Products

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Neuroscience-Neurodegeneration

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/cedrin.html

Solubility

10 mM in DMSO

Smiles

O=C1C2=C(O)C(C)=C(O)C=C2O[C@H](C3=CC(O)=C(O)C(O)=C3)[C@H]1O

Molecular Formula

C16H14O8

Molecular Weight

334.28

Precautions

P264-P280-P302+P352-P305+P351+P338-P362+P364-P405-P501

References & Citations

[1]Zhao Z, et, al. Cedrin identified from Cedrus deodara (Roxb.) G. Don protects PC12 cells against neurotoxicity induced by Aβ 1-42. Nat Prod Res. 2018 Jun;32 (12) :1455-1458.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

Curated Selection

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