Bevacizumab
Bevacizumab, a humanized IgG1 monoclonal antibody, specifically binds to all VEGF-A isoforms with high affinity.
Product Specifications
CAS Number
[216974-75-3]
Product Name Alternative
Anti-Human VEGF, Humanized Antibody
UNSPSC
12352203
Target
VEGFR
Type
Inhibitory Antibodies
Related Pathways
Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Bevacizumab.html
Purity
99.0
Solubility
H2O
Smiles
[Bevacizumab]
Molecular Weight
(146.56 kDa)
References & Citations
[1]Tan H, et al. 99mTc-labeled bevacizumab for detecting atherosclerotic plaque linked to plaque neovascularization and monitoring antiangiogenic effects of treatment in ApoE-/-mice. Sci Rep. 2017 Jun 14;7 (1) :3504.|[2]Wang Q, et al. Pharmacological characteristics and efficacy of a novel anti-angiogenic antibody FD006 in corneal neovascularization. BMC Biotechnol. 2014 Feb 27;14:17.|[3]Di Mauro C, et al. Hedgehog signalling pathway orchestrates angiogenesis in triple-negative breast cancers. Br J Cancer. 2017 May 23;116 (11) :1425-1435.
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4°C for 2 years, do not freeze
Scientific Category
Inhibitory Antibodies
Clinical Information
Launched
Citation 01
ACS Appl Mater Interfaces. 2024 Sep 11;16 (36) :47075-47088.|Adv Sci (Weinh) . 2023 Jun;10 (17) :e2205915.|Adv Sci (Weinh) . 2025 Sep;12 (33) :e02015.|Anal Chim Acta. 2021 Apr 15:1154:338306.|Apoptosis. 2025 Feb;30 (1-2) :16-34.|Autophagy. 2025 Mar;21 (3) :619-638.|Biochem Pharmacol. 2024 Feb:220:115991.|Biomaterials. 2024 Jul:308:122550.|Bone Res. 2024 Apr 10;12 (1) :24.|Cancer Res. 2024 Jun 4;84 (11) :1781-1798.|Cell Death Dis. 2020 Jan 23;11 (1) :55.|Cell Death Dis. 2025 Oct 24;16 (1) :751.|Cell Rep. 2023 Apr 5;42 (4) :112328.|Cell Signal. 2024 Aug 13:111346.|Commun Med (Lond) . 2025 Nov 18;5 (1) :478.|EBioMedicine. 2019 Sep.|Int J Biol Sci. 2022 Jan 1;18 (3) :942-955.|Int J Mol Sci. 2023 Jul 21;24 (14) :11766.|Int J Nanomedicine. 2024 Jul 16:19:7165-7183.|J Clin Oncol. 2024 Oct 30:JCO2401266.|J Ethnopharmacol. 2022 Jan 30:283:114667.|J Exp Clin Cancer Res. 2023 Mar 30;42 (1) :77.|J Extracell Vesicles. 2019 Jun 17;8 (1) :1629865. |J Mol Histol. 2025 Oct 22;56 (6) :350.|J Pharm Biomed Anal. 2021 May 10:198:114015.|J Transl Med. 2025 Apr 12;23 (1) :437.|J Transl Med. 2025 Jan 23;23 (1) :109.|Mater Today Bio. 2023 Sep 16:23:100800.|Mater Today Bio. 2025 May 29:33:101917.|Mol Carcinog. 2019 Dec;58 (12) :2316-2326.|Mol Pharm. 2025 Feb 3;22 (2) :972-983.|Nat Commun. 2025 Nov 18;16 (1) :10096.|Nucleic Acid Ther. 2020 Dec;30 (6) :365-378.|Pediatr Res. 2025 Oct 27.|Pharmacol Res. 2024 May 18:107218.|Phytomedicine. 2025 Oct 3:148:157358.|PLoS Pathog. 2023 Jan 18;19 (1) :e1011077.|Ren Fail. 2025 Dec;47 (1) :2561784.|Res Sq. 2025 May 29.|Research Square Preprint. 2020 Jun.|Research Square Print. 2022 Jun.|Sci Rep. 2025 Jul 1;15 (1) :20778.|Sci Rep. 2019 Nov 18;9 (1) :16954. |Theranostics. 2024 Jan 20;14 (3) :1312-1324.|Vascul Pharmacol. 2022 Dec:147:107126.|Brain Res. 2026 Jan 1:1870:150069.
Available Sizes
Curated Selection
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