Human SLAMF7 / CRACC / CD319 Protein, His Tag (HPLC verified)
Human SLAMF7, His Tag (SL7-H5225) is expressed from human 293 cells (HEK293) . It contains AA Ser 23 - Met 226 (Accession # Q9NQ25) .
Product Specifications
Background
SLAM family member 7 (SLAMF7) is also known as CD2-like receptor-activating cytotoxic cells (CRACC), Membrane protein FOAP-12, CD antigen CD319, Novel Ly9, Protein 19A, which is a single-pass type I membrane protein and a member of the CD2 family of cell surface receptors. SLAMF7 is expressed in spleen, lymph node, peripheral blood leukocytes, bone marrow, small intestine, stomach, appendix, lung and trachea. Isoform 1 of SLAMF7 mediates NK cell activation through a SH2D1A-independent extracellular signal-regulated ERK-mediated pathway. May play a role in lymphocyte adhesion. Isoform 3 of SLAMF7 does not mediate any NK cell activation.
Specifications
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 23.21 kDa. The protein migrates as 34-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
Q9NQ25
Expression Region
Ser 23 - Met 226
Host
HEK293
Target
SLAMF7
Conjugation
Unconjugated
Tag
C-6xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
0.1 EU per μg
Purity
95%
Bioactivity
Immobilized Human SLAMF7, His Tag (Cat. No. SL7-H5225) at 1 μg/mL (100 μL/well) can bind Anti-SLAMF7/CS1 Antibody, Human IgG1 with a linear range of 0.2-2 ng/mL (QC tested).
Format
Powder
Buffer
PBS, pH7.4
Additives
Trehalose
Molecular Weight
23.21 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
100ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/SL7-H5225.pdf
Species
Human
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