HIV-1 protease-IN-14
HIV-1 protease-IN-14 (compound 5ae) is a potent HIV-1 protease inhibitor with Ki values of 0.28, 56.9 nM for WT HIV-1 PR, R41T HIV-1 PR, respectively. HIV-1 protease-IN-14 shows low cytotoxicity[1].
Product Specifications
UNSPSC
12352211
Target
HIV Protease
Type
Reference compound
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/hiv-1-protease-in-14.html
Smiles
O=C(N[C@H]([C@H](O)CN(S(=O)(C1=CC=C(OC(C)C)C=C1)=O)CC(C)C)CC2=CC=CC=C2)O[C@@H]3[C@H]4[C@H](OCC4)OC3
Molecular Formula
C30H42N2O8S
Molecular Weight
590.73
References & Citations
[1]Ur Rehman MA, et al. Design, Synthesis, and Biological Evaluation of Darunavir Analogs as HIV-1 Protease Inhibitors. ACS Bio Med Chem Au. 2024 Sep 19;4 (5) :242-256.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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