Candicidin D

Candicidin D (CndD) is an antibiotic, which exhibits antifungal activity through interaction with steroids in cell membranes. Candicidin D inhibits S. cerevisiae, Candida albicans and other Candida spp. with MIC of 0.25-1 μg/mL in RPMI-1640 medium.

Product Specifications

CAS Number

[39372-30-0]

Product Name Alternative

CndD

UNSPSC

12352005

Target

Antibiotic; Fungal

Type

Reference compound

Related Pathways

Anti-infection

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/candicidin-d.html

Smiles

C[C@H]1/C=C/C=C\C=C\C=C\C=C\C=C\C=C\[C@H](O[C@H]2[C@@H](O)[C@@H](N)[C@H](O)[C@@H](C)O2)C[C@H](O)[C@H](C(O)=O)[C@@H](O)CC(C[C@@H](O)C[C@@H](O)C[C@@H](O)CC(CCCC(CC(O[C@]1([H])[C@H](C[C@@H]([C@@H](O)CC(C3=CC=C(N)C=C3)=O)C)C)=O)=O)=O)=O

Molecular Formula

C59H84N2O18

Molecular Weight

1109.30

References & Citations

[1]Borzyszkowska-Bukowska J, et al., Quest for the Molecular Basis of Improved Selective Toxicity of All-Trans Isomers of Aromatic Heptaene Macrolide Antifungal Antibiotics. Int J Mol Sci. 2021 Sep 18;22 (18) :10108.