Fmoc-D-Cit-OH

Fmoc-D-Cit-OH is citrulline with an Fmoc protecting group, which can be used to synthesize bioactive peptide mimetics, such as H-Dmt-D-Cit-Aba-b-Ala-NMe-30,50- (CF3) 2-Bn and H-Dmt-D-Cit-Aba-b-Ala-NMe-Bn with neurokinin-1 antagonist activity[1].

Product Specifications

CAS Number

[200344-33-8]

UNSPSC

12352209

Hazard Statement

H302, H315, H319, H335

Target

Amino Acid Derivatives

Type

Peptides

Related Pathways

Others

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/fmoc-d-cit-oh.html

Purity

99.81

Smiles

O=C(O)[C@@H](CCCNC(N)=O)NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Molecular Formula

C21H23N3O5

Molecular Weight

397.42

Precautions

H302, H315, H319, H335

References & Citations

[1]Guillemyn, et al. "Synthesis and biological evaluation of compact, conformationally constrained bifunctional opioid agonist–neurokinin-1 antagonist peptidomimetics." European journal of medicinal chemistry 92 (2015) : 64-77.