3,5-Difluoro-L-tyrosine

3,5-Difluoro-L-tyrosine is a functional, tyrosinase-resistant mimetic of tyrosine. 3,5-Difluoro-L-tyrosine can be used to analyze the substrate specificity of protein tyrosine phosphatases (PTPs) [1].

Product Specifications

CAS Number

[73246-30-7]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/3-5-difluoro-l-tyrosine.html

Purity

98.39

Solubility

H2O : 7 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

N[C@@H](CC1=CC(F)=C(O)C(F)=C1)C(O)=O

Molecular Formula

C9H9F2NO3

Molecular Weight

217.17

Precautions

H302, H315, H319, H335

References & Citations

[1]Bhaskar Gopishetty, et al. Synthesis of 3,5-difluorotyrosine-containing peptides: application in substrate profiling of protein tyrosine phosphatases. Org Lett. 2008 Oct 16;10 (20) :4605-8.