PTK7/β-catenin-IN-6
PTK7/β-catenin-IN-6 (Compound 03653) is an inhibitor for PTK7/β-catenin interaction, which inhibits the Wnt signaling pathway, and exhibits an anticancer activity against colorectal cancer (CRC) [1].
Product Specifications
CAS Number
[1219439-82-3]
UNSPSC
12352005
Target
Wnt; β-catenin
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ptk7-β-catenin-in-6.html
Purity
96.60
Solubility
DMSO : 73.33 mg/mL (ultrasonic)
Smiles
O=C(N1C2=C(NC(C1CC(NC3=CC=C(C(Cl)=C3)Cl)=O)=O)C=CC=C2)/C=C/C4=CC=CC=C4
Molecular Formula
C25H19Cl2N3O3
Molecular Weight
480.34
References & Citations
[1]Ganier L, et al., Discovery of Small-Molecule Inhibitors of the PTK7/β-Catenin Interaction Targeting the Wnt Signaling Pathway in Colorectal Cancer. ACS Chem Biol. 2022 May 20;17 (5) :1061-1072.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
