IL-15-IN-1
IL-15-IN-1 (compound 76) is a potent and selective Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells with an IC50 of 0.8 μM[1].
Product Specifications
CAS Number
[1831830-20-6]
UNSPSC
12352005
Target
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/IL-15-IN-1.html
Purity
99.79
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CN1C(CC2=NN(C)C(C3=CC=CC=C32)=O)=NN=C1SCCCCCCCC(NC4=CC=CC(C(OCC)=O)=C4)=O
Molecular Formula
C30H36N6O4S
Molecular Weight
576.71
References & Citations
[1]Quéméner A, et al. Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. J Med Chem. 2017 Jul 27;60 (14) :6249-6272.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-15
Available Sizes
Curated Selection
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