IL-15-IN-1
Product Specifications
UNSPSC Description
IL-15-IN-1 (compound 76) is a potent and selective Interleukin 15 (IL-15) inhibitor, inhibiting the proliferation of IL-15-dependent cells with an IC50 of 0.8 μM[1].
Target Antigen
Interleukin Related
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/IL-15-IN-1.html
Purity
99.42
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CN1C(CC2=NN(C)C(C3=CC=CC=C32)=O)=NN=C1SCCCCCCCC(NC4=CC=CC(C(OCC)=O)=C4)=O
Molecular Weight
576.71
References & Citations
[1]Quéméner A, et al. Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization. J Med Chem. 2017 Jul 27;60(14):6249-6272.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-102049/IL-15-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-102049/IL-15-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1831830-20-6
Available Sizes
Curated Selection
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