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IAV-IN-3

IAV-IN-3 (Compound (R, S) -16s) is an anti-influenza A virus (IAV) agent (EC50 = 0.134 μM) with weak cytotoxicity (CC50 = 15.35 μM for MDCK cells) . IAV-IN-3 inhibits IAV polymerase with an IC50 of 0.045 μM[1].

Product Specifications

CAS Number

3049492-11-4

UNSPSC

12352005

Target

Influenza Virus

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/iav-in-3.html

Smiles

O=C1N2[C@H](CCC2)CN([C@H]3C(C=CC(F)=C4F)=C4CSC5=C3C=CC=C5)N(C1=C6O)C=CC6=O

Molecular Formula

C25H21F2N3O3S

Molecular Weight

481.51

References & Citations

[1]Zhang L, et al. Design and synthesis of 7-membered lactam fused hydroxypyridinones as potent metal binding pharmacophores (MBPs) for inhibiting influenza virus PAN endonuclease. Eur J Med Chem. 2024 Jul 1;276:116639.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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