IAV-IN-3
IAV-IN-3 (Compound (R, S) -16s) is an anti-influenza A virus (IAV) agent (EC50 = 0.134 μM) with weak cytotoxicity (CC50 = 15.35 μM for MDCK cells) . IAV-IN-3 inhibits IAV polymerase with an IC50 of 0.045 μM[1].
Product Specifications
CAS Number
3049492-11-4
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/iav-in-3.html
Smiles
O=C1N2[C@H](CCC2)CN([C@H]3C(C=CC(F)=C4F)=C4CSC5=C3C=CC=C5)N(C1=C6O)C=CC6=O
Molecular Formula
C25H21F2N3O3S
Molecular Weight
481.51
References & Citations
[1]Zhang L, et al. Design and synthesis of 7-membered lactam fused hydroxypyridinones as potent metal binding pharmacophores (MBPs) for inhibiting influenza virus PAN endonuclease. Eur J Med Chem. 2024 Jul 1;276:116639.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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