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Polθ-IN-6

Polθ-IN-6 (Compound 89) is a DNA polymerase theta (Polθ) inhibitor. Polθ-IN-6 has antitumor activity[1].

Product Specifications

CAS Number

3058496-94-6

UNSPSC

12352005

Target

DNA/RNA Synthesis

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/polθ-in-6.html

Smiles

O=C(C1=CN=C(C)C=C1C2=C(OC)C=CC=C2)NC3=NC4=C(S3)C=C(C5OCCC5)C=C4

Molecular Formula

C25H23N3O3S

Molecular Weight

445.53

References & Citations

[1]Michael H Reutershan, et al. Biaryl derivatives and related uses. WO2024211834A1.2024-10-10.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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