Δ17-6-keto Prostaglandin F1α
Δ17-6-keto Prostaglandin F1α (Δ17-6-keto PGF1α) is a cyclooxygenase (COX) product of eicosapentaenoic acid (EPA) in various tissues such as seminal vesicles, lung, Polymorphonuclear leukocytes, and ocular tissues. Δ17-6-keto PGF1α and other 3-series COX products from EPA, such as PGF3α, PGE3, and thromboxane B3, may be involved in the reduced incidence of glaucoma in patients on a marine-rich (EPA-rich) diet.
Product Specifications
CAS Number
[68324-95-8]
Product Name Alternative
ω-3 6-keto PGF2α
UNSPSC
12352211
Hazard Statement
H225-H319-H336
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/17-6-keto-prostaglandin-f1α.html
Smiles
O[C@@H]1[C@@H]([C@H]([C@@H](C1)O)/C=C/[C@H](C/C=C\CC)O)CC(CCCCC(O)=O)=O
Molecular Formula
C20H32O6
Molecular Weight
368.46
Precautions
P210-P233-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P370+P378-P403+P233-P403+P235-P405-P501
References & Citations
[1]Kulkarni, et al. Eicosapentaenoic acid metabolism in cynomolgus and rhesus conjunctiva and eyelid. J. Ocul. Pharmacol. 3 (4), 349-356 (1987) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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