IDD-8E
IDD-8E is an effective anti-pseudomonal agent (MIC =4.4 μM) with no cytotoxicity. IDD-8E shows significant pseudomonal killing and disruption of pseudomonal biofilm. IDD-8E binds to the ATP-binding pocket of WaaP and also inhibits other ESKAPE pathogens. [1]
Product Specifications
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/idd-8e.html
Solubility
10 mM in DMSO
Smiles
CC(C=C1)=CC2=C1N=C(NC3=NC(C4=CC(OC)=C(OC)N=C4)=CC(N3)=O)N=C2C
Molecular Formula
C21H20N6O3
Molecular Weight
404.42
References & Citations
[1]Rakshit M et al. Uncovering the potentiality of quinazoline derivatives against Pseudomonas aeruginosa with antimicrobial synergy and SAR analysis. J Antibiot. 2024 MAR
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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