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Enbezotinib (enantiomer)

Enbezotinib (enantiomer) (Compound 44) is the enantiomer form of Enbezotinib (HY-145565) . Enbezotinib is an inhibitor of RET[1].

Product Specifications

CAS Number

[2359650-19-2]

Product Name Alternative

TPX-0046 (enantiomer)

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

RET

Type

Reference compound

Related Pathways

Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/enbezotinib-enantiomer.html

Purity

99.72

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

FC(C=C1CN2C3=NC4=C5C=NN4C=C3O[C@@]6([H])[C@]2([H])CCC6)=CN=C1O[C@H](C)CNC5=O

Molecular Formula

C21H21FN6O3

Molecular Weight

424.43

Precautions

P261-P280-P302+P352

References & Citations

[1]Evan W. ROGERS, et, al. Macrocyclic compounds for treating disease. Patent. WO2019126121 A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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