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Reboxetine (mesylate) (Standard)

Reboxetine (mesylate) (Standard) is the analytical standard of Reboxetine (mesylate) . This product is intended for research and analytical applications. Reboxetine mesylate (FCE20124 mesylate) is a potent, selective, and specific noradrenaline reuptake inhibitor (NARI) for the research of depression. Reboxetine mesylate inhibits the uptake of norepinephrine, with a Ki of 8 nM[1].

Product Specifications

CAS Number

98769-84-7

Product Name Alternative

FCE20124 (mesylate) (Standard) ; PNU155950E (mesylate) (Standard)

UNSPSC

12352005

Target

Adrenergic Receptor; Reference Standards

Type

Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Assay Protocol

https://www.medchemexpress.com/reboxetine-mesylate-standard.html

Smiles

CS(=O)(O)=O.CCOC1=C(C=CC=C1)O[C@]([C@@]2([H])CNCCO2)([H])C3=CC=CC=C3

Molecular Formula

C20H27NO6S

Molecular Weight

409.50

References & Citations

[1]Wong, E.H., et al., Reboxetine: a pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor. Biol Psychiatry, 2000. 47 (9) : p. 818-29.|[2]Versiani, M., et al., Reboxetine, a unique selective NRI, prevents relapse and recurrence in long-term treatment of major depressive disorder. J Clin Psychiatry, 1999. 60 (6) : p. 400-6.|[3]M Leskiewicz, et al. Antidepressants attenuate the dexamethasone-induced decrease in viability and proliferation of human neuroblastoma SH-SY5Y cells: a involvement of extracellular regulated kinase (ERK1/2) . Neurochem Int. 2013 Nov;63 (5) :354-62.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Available Sizes

Frequently Asked Questions

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