Ac-Trp-Glu-His-Asp-AMC
Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1[1].
Product Specifications
CAS Number
[189275-74-9]
Product Name Alternative
AC-WEHD-AMC
UNSPSC
12352209
Target
Caspase
Type
Peptides
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/ac-trp-glu-his-asp-amc.html
Purity
99.84
Solubility
DMSO : ≥ 100 mg/mL
Smiles
CC(C1=CC=C(C=C1O2)NC([C@H](CC(O)=O)NC([C@H](CC3=CN=CN3)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=CC2=O
Molecular Formula
C38H40N8O11
Molecular Weight
784.77
References & Citations
[1]Kindermann M, et al. Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe. Chem Biol. 2010 Sep 24;17 (9) :999-1007.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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