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Ac-Trp-Glu-His-Asp-AMC

Ac-Trp-Glu-His-Asp-AMC (AC-WEHD-AMC) is a potent fluorogenic substrate of caspase-1[1].

Product Specifications

CAS Number

[189275-74-9]

Product Name Alternative

AC-WEHD-AMC

UNSPSC

12352209

Target

Caspase

Type

Peptides

Related Pathways

Apoptosis

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/ac-trp-glu-his-asp-amc.html

Purity

99.84

Solubility

DMSO : ≥ 100 mg/mL

Smiles

CC(C1=CC=C(C=C1O2)NC([C@H](CC(O)=O)NC([C@H](CC3=CN=CN3)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)CC4=CNC5=CC=CC=C45)=O)=O)=O)=O)=CC2=O

Molecular Formula

C38H40N8O11

Molecular Weight

784.77

References & Citations

[1]Kindermann M, et al. Selective and sensitive monitoring of caspase-1 activity by a novel bioluminescent activity-based probe. Chem Biol. 2010 Sep 24;17 (9) :999-1007.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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