(5S,6R) -DiHETEs
(5S,6R) -DiHETEs is the isomer of (5S,6R) -DiHETE. (5S,6R) -DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R) -DiHETE can induce guinea pig isolated ileum contraction with an EC50 of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists[1].
Product Specifications
CAS Number
129263-59-8
Product Name Alternative
(5S,6R) - (11E) -DiHETE
UNSPSC
12352211
Target
Leukotriene Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/5s-6r-dihetes.html
Solubility
10 mM in DMSO
Smiles
CCCCC/C=C\C/C=C/C=C/C=C/[C@@H](O)[C@@H](O)CCCC(O)=O
Molecular Formula
C20H32O4
Molecular Weight
336.47
References & Citations
[1]Muller A, et al. Comparative biological activities of the four synthetic (5,6) -dihete isomers. Prostaglandins. 1989 Dec;38 (6) :635-44.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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