2-Methoxyphenyl dihydrouracil
2-Methoxyphenyl dihydrouracil (Compound 13) is a CRBN ligand, and can be used for synthesis of PROTACs[1].
Product Specifications
CAS Number
[2377643-33-7]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Ligands for E3 Ligase
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/2-methoxyphenyl-dihydrouracil.html
Purity
98.0
Smiles
O=C(O)C1=CC=C(OC)C(N(C(N2)=O)CCC2=O)=C1
Molecular Formula
C12H12N2O5
Molecular Weight
264.24
Precautions
H302, H315, H319, H335
References & Citations
[1]Wang K, et al. Design, synthesis, and bioevaluation of SOS1 PROTACs derived from pyrido[2,3-d]pyrimidin-7-one-based SOS1 inhibitor. Bioorg Med Chem Lett. 2024 Jul 15;107:129780.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Cereblon
Available Sizes
Curated Selection
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