MSC-1254
MSC-1254 is a reversible, selective and covalent TEAD1 inhibitor. MSC-1254 can be used for the study of cancer[1].
Product Specifications
UNSPSC
12352101
Target
YAP
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/msc-1254.html
Smiles
O=C(C1=CN=C2C=CC(F)=CN12)NCC3=C(C=C(C=C3)OC4=CC=C(C=C4)F)N5CCS(=O)(CC5)=O
Molecular Formula
C25H22F2N4O4S
Molecular Weight
512.53
References & Citations
[1]Emma Carswell, et al. Discovery of reversible and covalent TEAD 1 selective inhibitors MSC-1254 and MSC-5046 based on one scaffold. Bioorg Med Chem Lett. 2024 Oct 5:114:129981.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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