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NRAM2 rabbit pAb

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010],

Product Specifications

Background

This gene encodes a member of the solute carrier family 11 protein family. The product of this gene transports divalent metals and is involved in iron absorption. Mutations in this gene are associated with hypochromic microcytic anemia with iron overload. A related solute carrier family 11 protein gene is located on chromosome 2. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Apr 2010]

Product Name Alternative

Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1)

UniProt

P49281

Swiss Prot

P49281

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human NRAM2 AA range: 474-524

Target

NRAM2

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Molecular Weight

60kD

Storage Conditions

-20°C/1 year

Observed Molecular Weight

60kD

Fragment

IgG

Subcellular Location

[Isoform 2]: Cell membrane ; Multi-pass membrane protein . Early endosome .; Endosome membrane ; Multi-pass membrane protein . Mitochondrion outer membrane ; Multi-pass membrane protein. Cell membrane ; Multi-pass membrane protein . Also found in extracellular vesicles different from exosomes. .

Other Product Names

Natural resistance-associated macrophage protein 2 (NRAMP 2) (Divalent cation transporter 1) (Divalent metal transporter 1) (DMT-1)

Gene ID (Human)

4891

Available Sizes

Curated Selection

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