Cf1743
Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK) [1].
Product Specifications
CAS Number
319425-66-6
UNSPSC
12352005
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/cf1743.html
Solubility
10 mM in DMSO
Smiles
O=C1N=C2C(C=C(C3=CC=C(C=C3)CCCCC)O2)=CN1[C@@H](C[C@@H]4O)O[C@@H]4CO
Molecular Formula
C22H26N2O5
Molecular Weight
398.45
References & Citations
[1]McGuigan C, et al. 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Bioorg Med Chem Lett. 2009 Nov 15;19 (22) :6264-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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