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Cf1743

Cf1743 is a potent anti-varicella-zoster virus (VZV) bicyclic nucleoside analogue. Cf1743 has antiviral activity, with an IC50 of 3.3 μM for VZV thymidine kinase (TK) [1].

Product Specifications

CAS Number

319425-66-6

UNSPSC

12352005

Target

Nucleoside Antimetabolite/Analog

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/cf1743.html

Solubility

10 mM in DMSO

Smiles

O=C1N=C2C(C=C(C3=CC=C(C=C3)CCCCC)O2)=CN1[C@@H](C[C@@H]4O)O[C@@H]4CO

Molecular Formula

C22H26N2O5

Molecular Weight

398.45

References & Citations

[1]McGuigan C, et al. 2'-Fluorosugar analogues of the highly potent anti-varicella-zoster virus bicyclic nucleoside analogue (BCNA) Cf 1743. Bioorg Med Chem Lett. 2009 Nov 15;19 (22) :6264-7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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