BTK, Human (P. pastoris, His)

The BTK protein is a key non-receptor tyrosine kinase that is essential for B lymphocyte development and signaling. After BCR activation, BTK initiates a cascade reaction, phosphorylates PLCG2 and activates downstream pathways, affecting calcium mobilization and PKC activation. BTK Protein, Human (P. pastoris, His) is the recombinant human-derived BTK protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of BTK Protein, Human (P. pastoris, His) is 659 a.a., with molecular weight of 78.2 kDa.

AAVILESIFL KRSQQKKKTS PLNFKKRLFL LTVHKLSYYE YDFERGRRGS KKGSIDVEKI TCVETVVPEK NPPPERQIPR RGEESSEMEQ ISIIERFPYP FQVVYDEGPL YVFSPTEELR KRWIHQLKNV IRYNSDLVQK YHPCFWIDGQ YLCCSQTAKN AMGCQILENR NGSLKPGSSH RKTKKPLPPT PEEDQILKKP LPPEPAAAPV STSELKKVVA LYDYMPMNAN DLQLRKGDEY FILEESNLPW WRARDKNGQE GYIPSNYVTE AEDSIEMYEW YSKHMTRSQA EQLLKQEGKE GGFIVRDSSK AGKYTVSVFA KSTGDPQGVI RHYVVCSTPQ SQYYLAEKHL FSTIPELINY HQHNSAGLIS RLKYPVSQQN KNAPSTAGLG YGSWEIDPKD LTFLKELGTG QFGVVKYGKW RGQYDVAIKM IKEGSMSEDE FIEEAKVMMN LSHEKLVQLY GVCTKQRPIF IITEYMANGC LLNYLREMRH RFQTQQLLEM CKDVCEAMEY LESKQFLHRD LAARNCLVND QGVVKVSDFG LSRYVLDDEY TSSVGSKFPV RWSPPEVLMY SKFSSKSDIW AFGVLMWEIY SLGKMPYERF TNSETAEHIA QGLRLYRPHL ASEKVYTIMY SCWHEKADER PTFKILLSNI LDVMDEES