VMIP-II (1-21) (TFA)
VMIP-II (1-21) (NT21MP) TFA is an inhibitor of CXCR4. vMIP-II (1-21) TFA interacts broadly with CC and CXC chemokine receptors. vMIP-II (1-21) TFA inhibits CXCR4 by competing with 125I-SDF-1R for binding sites (IC50=190 nM) [1].
Product Specifications
Product Name Alternative
NT21MP (TFA) ; V1 peptide (TFA)
UNSPSC
12352209
Target
CXCR
Type
Peptides
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-anti-virus
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/vmip-ii-1-21-tfa.html
Purity
99.92
Solubility
H2O : ≥ 100 mg/mL
Smiles
O=C(NCC(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CNC=N3)C(N[C@@H](CCCNC(N)=N)C(N4[C@@H](CCC4)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CS)C(N[C@@H](CS)C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CC5=CC=C(C=C5)O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N6[C@@H](CCC6)C(N[C@@H](CC(C)C)C(N7[C@@H](CCC7)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(C)C)N.OC(C(F)(F)F)=O.[x]
Molecular Formula
C108H169N33O27S2.xC2HF3O2
Molecular Weight
2425.84 (free base)
References & Citations
[1]Zhou N, ey al. A novel peptide antagonist of CXCR4 derived from the N-terminus of viral chemokine vMIP-II. Biochemistry. 2000 Apr 4;39 (13) :3782-7.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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