Nidurufin

Nidurufin is a potent cell cycle inhibitor with antitumor activity.Nidurufin induces in vitro cell cycle arrest at G2/M transition in the K562 cell line in a concentration and time dependent manner (IC50=12.6 μM) [1].

Product Specifications

CAS Number

[28458-23-3]

UNSPSC

12352005

Target

Others

Type

Natural Products

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nidurufin.html

Solubility

10 mM in DMSO

Smiles

OC1=C2C(O[C@@]3(O[C@H]2[C@H](CC3)O)C)=CC4=C1C(C5=C(O)C=C(O)C=C5C4=O)=O

Molecular Formula

C20H16O8

Molecular Weight

384.34

References & Citations

[1]Hong Ren, et al.Nidurufin as a new cell cycle inhibitor from marine-derived fungus Penicillium flavidorsum SHK1-27. Arch Pharm Res. 2011 Jun;34 (6) :901-5.