Nidurufin
Nidurufin is a potent cell cycle inhibitor with antitumor activity.Nidurufin induces in vitro cell cycle arrest at G2/M transition in the K562 cell line in a concentration and time dependent manner (IC50=12.6 μM) [1].
Product Specifications
CAS Number
[28458-23-3]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nidurufin.html
Solubility
10 mM in DMSO
Smiles
OC1=C2C(O[C@@]3(O[C@H]2[C@H](CC3)O)C)=CC4=C1C(C5=C(O)C=C(O)C=C5C4=O)=O
Molecular Formula
C20H16O8
Molecular Weight
384.34
References & Citations
[1]Hong Ren, et al.Nidurufin as a new cell cycle inhibitor from marine-derived fungus Penicillium flavidorsum SHK1-27. Arch Pharm Res. 2011 Jun;34 (6) :901-5.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Curated Selection
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