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Deserpidine (Standard)

Deserpidine (Standard) is the analytical standard of Deserpidine. This product is intended for research and analytical applications. Deserpidine (Harmonyl) is an alkaloid isolated from the root of Rauwolfia canescens related to Reserpine. Deserpidine is used as an antihypertensive agent and a tranquilizer. Deserpidine is a competitive angiotensin converting enzyme (ACE) inhibitor. Deserpidine also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex[1][2][3].

Product Specifications

CAS Number

131-01-1

Product Name Alternative

Harmonyl (Standard)

UNSPSC

12352005

Target

Angiotensin-converting Enzyme (ACE) ; Reference Standards

Type

Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/deserpidine-standard.html

Smiles

COC([C@H]1[C@@]2([H])C[C@]3([H])C4=C(CCN3C[C@@]2([H])C[C@@H](OC(C5=CC(OC)=C(OC)C(OC)=C5)=O)[C@@H]1OC)C6=CC=CC=C6N4)=O

Molecular Formula

C32H38N2O8

Molecular Weight

578.65

References & Citations

[1]Varchi G, et al. Synthesis of deserpidine from reserpine. J Nat Prod. 2005 Nov;68 (11) :1629-31.|[2]Zhang H, et al. Liquid chromatography/tandem mass spectrometry method for the quantification of deserpidine in human plasma: Application to a pharmacokinetic study. J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Oct 1;877 (27) :3221-5.|[3]Fulton SC, et al. Comparison of the effectiveness of deserpidine, reserpine, and alpha-methyltyrosine on brain biogenic amines. Fed Proc. 1976 Dec;35 (14) :2558-62.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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