Bz-Dab (NBD) -AwFpP-Nle-NH2
Bz-Dab (NBD) -AwFpP-Nle-NH2 (Compound 5B) is a potent fluorescent antagonist of NK2 receptor, with a pKi of 8.87 nM (Ex=340 nm, Em=505 nm) [1].
Product Specifications
CAS Number
161238-74-0
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/bz-dab-nbd-awfpp-nle-nh2.html
Smiles
O=C(C1=CC=CC=C1)N[C@H](C(N[C@@H](C)C(N[C@@H](C(N[C@@H](CC2=CC=CC=C2)C(N3[C@H](CCC3)C(N4[C@@H](CCC4)C(N[C@H](C(N)=O)CCCC)=O)=O)=O)=O)CC5=CNC6=CC=CC=C56)=O)=O)CCNC7=CC=C(C8=NON=C87)[N+]([O-])=O
Molecular Formula
C56H65N13O11
Molecular Weight
1096.20
References & Citations
[1]Bradshaw CG, et al. Synthesis and characterization of selective fluorescent ligands for the neurokinin NK2 receptor. J Med Chem. 1994 Jun 24;37 (13) :1991-5.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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