Aminopeptidase P2, Human (HEK293, His)

Aminopeptidase P2 Protein, Human (HEK293, His), a recombinant human Aminopeptidase P2 produced in HEK293 cells, has a His tag at the C-terminus. Aminopeptidase P2 is an aminoacylproline hydrolase that specifically removes the N-terminal amino acid from peptides with a penultimate prolyl residue[1].

HTKPVDLGGQ DVRNCSTNPP YLPVTVVNTT MSLTALRQQM QTQNLSAYII PGTDAHMNEY IGQHDERRAW ITGFTGSAGT AVVTMKKAAV WTDSRYWTQA ERQMDCNWEL HKEVGTTPIV TWLLTEIPAG GRVGFDPFLL SIDTWESYDL ALQGSNRQLV SITTNLVDLV WGSERPPVPN QPIYALQEAF TGSTWQEKVS GVRSQMQKHQ KVPTAVLLSA LEETAWLFNL RASDIPYNPF FYSYTLLTDS SIRLFANKSR FSSETLSYLN SSCTGPMCVQ IEDYSQVRDS IQAYSLGDVR IWIGTSYTMY GIYEMIPKEK LVTDTYSPVM MTKAVKNSKE QALLKASHVR DAVAVIRYLV WLEKNVPKGT VDEFSGAEIV DKFRGEEQFS SGPSFETISA SGLNAALAHY SPTKELNRKL SSDEMYLLDS GGQYWDGTTD ITRTVHWGTP SAFQKEAYTR VLIGNIDLSR LIFPAATSGR MVEAFARRAL WDAGLNYGHG TGHGIGNFLC VHEWPVGFQS NNIAMAKGMF TSIEPGYYKD GEFGIRLEDV ALVVEAKTKY PGSYLTFEVV SFVPYDRNLI DVSLLSPEHL QYLNRYYQTI REKVGPELQR RQLLEEFEWL QQHTEPLAAH HHHHH

[1]Erşahin C, et al. Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions. Arch Biochem Biophys. 2005 Mar 15;435(2):303-10.|[2]Li F, et al. XPNPEP2 is associated with lymph node metastasis in prostate cancer patients. Sci Rep. 2019 Jul 11;9(1):10078.