Antibacterial agent 246
Antibacterial agent 246 (compound A33) is a antibacterial agent and has minimum inhibitory concentrations (MICs) of 0.5-4 μg/mL against twenty-three Gram-positive bacteria. Antibacterial agent 246 in combination with Polymyxin E E inhibits the growth of various Gram-negative bacteria with the fractional inhibitory concentration index of 0.066[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Antibiotic; Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antibacterial-agent-246.html
Smiles
C/C(C1=CSC(NC2=CC(C(F)(F)F)=CC(F)=C2)=N1)=N\NC3=NC=CC=C3
Molecular Formula
C17H13F4N5S
Molecular Weight
395.38
References & Citations
[1]Chen Y, et al. Novel 2-aminothiazole analogues both as polymyxin E synergist and antimicrobial agent against multidrug-resistant Gram-positive bacteria. Eur J Med Chem. Published online September 16, 2024.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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