PPQ-581
PPQ-581 is an anti-influenza agent with an EC50 of 1 μM for preventing virus-induced cytopathic effects. PPQ-581 inhibits viral protein synthesis. PPQ-581 blocks the RNP nuclear export and cytoplasmic RNP aggregation[1].
Product Specifications
CAS Number
950381-32-5
UNSPSC
12352005
Target
Influenza Virus
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/ppq-581.html
Smiles
O=C1C2=C(N3C(C(C4=C(F)C=CC=C4)OCC3(C)C)=C2N(C)C(N1C)=O)C5=CC=CC=C5
Molecular Formula
C25H24FN3O3
Molecular Weight
433.47
References & Citations
[1]Lin MI, et al. Synthesis and inhibitory effects of novel pyrimido-pyrrolo-quinoxalinedione analogues targeting nucleoproteins of influenza A virus H1N1. Eur J Med Chem. 2015 Sep 18;102:477-86.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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