AMG133 peptide payload
AMG133 peptide payload is a GLP-1 agonist that can be used as a peptide linker conjugate of Maridebart cafraglutide (AMG133).
Product Specifications
UNSPSC
12352209
Target
GCGR
Type
Peptides
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/amg133-peptide-payload.html
Purity
95.57
Solubility
DMSO : 50 mg/mL
Smiles
O=C([C@@H](N)CC1=CNC=N1)NC(C)(C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(NCC(NCC(NCC(NCC(NCC(N[C@H](C(NCC(NCC(NCC(NCC(N[C@H](C(NCC(NCC(NCC(NCC(N[C@H](C(N[C@H](C(N)=O)CCCCNC(CBr)=O)=O)CO)=O)=O)=O)=O)=O)CO)=O)=O)=O)=O)=O)CO)=O)=O)=O)=O)=O)=O)=O)=O)CCCCN)=O)C(C)C)=O)CC(C)C)=O)CC2=CNC3=CC=CC=C23)=O)C)=O)[C@H](CC)C)=O)CC4=CC=CC=C4)=O)CCC(O)=O)=O)CCCCN)=O)C)=O)C)=O)CCC(N)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)CC(C)C)=O)CC5=CC=C(O)C=C5)=O)CO)=O)CO)=O)CC6=CC=C(O)C=C6)=O)CC(O)=O)=O)CO)=O)[C@@H](C)O)=O)CC7=CC=CC=C7)=O)[C@@H](C)O)=O)=O)CCC(O)=O)=O)C
Molecular Formula
C196H290BrN55O69
Molecular Weight
4600.70
References & Citations
[1]Véniant MM, et al. A GIPR antagonist conjugated to GLP-1 analogues promotes weight loss with improved metabolic parameters in preclinical and phase 1 settings. Nat Metab. 2024 Feb;6 (2) :290-303.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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