Chloranthalactone B
Chloranthalactone B, a lindenane-type sesquiterpenoid, is a nature product that could be isolated from Chinese medicinal herb Sarcandra glabra. Chloranthalactone B inhibits the production of inflammatory mediators by inhibiting the AP-1 and p38 MAPK pathways[1].
Product Specifications
CAS Number
66395-03-7
UNSPSC
12352005
Target
AP-1; COX; Interleukin Related; NO Synthase; p38 MAPK; TNF Receptor
Type
Natural Products
Related Pathways
Apoptosis; Immunology/Inflammation; MAPK/ERK Pathway
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/chloranthalactone-b.html
Solubility
10 mM in DMSO
Smiles
C[C@@]12[C@@]3([H])[C@]4(O3)C(C[C@@]1([H])C([C@]5([H])[C@@]2([H])C5)=C)=C(C(O4)=O)C
Molecular Formula
C15H16O3
Molecular Weight
244.29
References & Citations
[1]Li X, et, al. Anti-Inflammatory Effects of Chloranthalactone B in LPS-Stimulated RAW264.7 Cells. Int J Mol Sci. 2016 Nov 22;17 (11) :1938.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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