Anticancer agent 236
Anticancer agent 236 (compound JP-8g) is a broad-spectrum anticancer agent that has toxic effects on several cancer cell lines with IC50 values of 6.925 μM (MDA), 6.296 μM (U937), 6.548 μM (Jurkat), 6.373 μM (Hela), and 10.381 μM (EJ) [1].
Product Specifications
CAS Number
1356340-69-6
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/anticancer-agent-236.html
Smiles
O=C(N(C1=C2C=CC=C1F)CC=C)[C@@]32C4=C(OC(N=C(N5C(C)=O)C)=C3C5=O)C6=CC(F)=CC=C6OC4=O
Molecular Formula
C27H17F2N3O6
Molecular Weight
517.44
References & Citations
[1]Jiang X, et al. Core scaffold‐inspired concise synthesis of chiral spirooxindole‐pyranopyrimidines with broad‐spectrum anticancer potency[J]. Advanced Synthesis & Catalysis, 2012, 354 (5) : 917-925.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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