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Anticancer agent 236

Anticancer agent 236 (compound JP-8g) is a broad-spectrum anticancer agent that has toxic effects on several cancer cell lines with IC50 values of 6.925 μM (MDA), 6.296 μM (U937), 6.548 μM (Jurkat), 6.373 μM (Hela), and 10.381 μM (EJ) [1].

Product Specifications

CAS Number

1356340-69-6

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/anticancer-agent-236.html

Smiles

O=C(N(C1=C2C=CC=C1F)CC=C)[C@@]32C4=C(OC(N=C(N5C(C)=O)C)=C3C5=O)C6=CC(F)=CC=C6OC4=O

Molecular Formula

C27H17F2N3O6

Molecular Weight

517.44

References & Citations

[1]Jiang X, et al. Core scaffold‐inspired concise synthesis of chiral spirooxindole‐pyranopyrimidines with broad‐spectrum anticancer potency[J]. Advanced Synthesis & Catalysis, 2012, 354 (5) : 917-925.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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