Sphingosine kinase 2 Active Human

<strong>Sphingosine kinase 2 Active Human</strong>_x000D_ <strong>Catalog number:</strong> B2019699_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 10 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> 69.5 kDa_x000D_ <strong>Supplied as:</strong> Solution_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> −70°C_x000D_ <strong>Keywords:</strong> SK2, SPHK2, SPK 2_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Yokoyama S, Koo I, Aibara D, Tian Y, Murray IA, Collins SL, Coslo DM, Kono M, Peters JM, Proia RL, Gonzalez FJ, Perdew GH, Patterson AD. Sphingosine Kinase 2 Regulates Aryl Hydrocarbon Receptor Nuclear Translocation and Target Gene Activation Adv Sci (Weinh). 2024 Oct;11(40):e2400794._x000D_ 2: Hamdan N, Bhagirath AY, Batista EL Jr. Sphingosine kinase activity and sphingosine-1-phosphate in the inflamed human periodontium Oral Dis. 2023 Jan;29(1):265-273._x000D_ 3: Weigel C, Maczis MA, Palladino END, Green CD, Maceyka M, Guo C, Wang XY, Dozmorov MG, Milstien S, Spiegel S. Sphingosine Kinase 2 in Stromal Fibroblasts Creates a Hospitable Tumor Microenvironment in Breast Cancer Cancer Res. 2023 Feb 15;83(4):553-567._x000D_ 4: Mu Y, Wang J, Li G. Sphingosine kinase-2 silencing modulates sensitivity of HT-29 human colorectal cancer cells to paclitaxel-induced cell death through altering apoptosis-related proteins Chem Biol Drug Des. 2023 Aug;102(2):255-261._x000D_ 5: Pyne NJ, El Buri A, Adams DR, Pyne S. Sphingosine 1-phosphate and cancer Adv Biol Regul. 2018 May;68:97-106._x000D_ 6: Rohrbach T, Maceyka M, Spiegel S. Sphingosine kinase and sphingosine-1-phosphate in liver pathobiology Crit Rev Biochem Mol Biol. 2017 Oct;52(5):543-553._x000D_ 7: Ding X, Zhang X, Cao J, Chen S, Chen Y, Yuan K, Chen B, Yang G, Li S, Yang J, Wang G, Tacke F, Lan T. Sphingosine Kinase 1 Aggravates Liver Fibrosis by Mediating Macrophage Recruitment and Polarization Cell Mol Gastroenterol Hepatol. 2024;18(6):101406._x000D_ 8: Aji G, Jiang S, Obulkasim H, Lu Z, Wang W, Xia P. Sphingosine kinase 2 regulates insulin receptor trafficking in hepatocytes Exp Biol Med (Maywood). 2023 Jan;248(1):44-51._x000D_ 9: Zhou J, Chen J, Yu H. Targeting sphingosine kinase 2 by ABC294640 inhibits human skin squamous cell carcinoma cell growth Biochem Biophys Res Commun. 2018 Mar 4;497(2):535-542._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/36975444">10: Wu J, Fan S, Feinberg D, Wang X, Jabbar S, Kang Y. Inhibition of Sphingosine Kinase 2 Results in PARK2-Mediated Mitophagy and Induces Apoptosis in Multiple Myeloma Curr Oncol. 2023 Mar 4;30(3):3047-3063. </a>_x000D_ _x000D_ <strong>Products Related to Sphingosine kinase 2 Active Human can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>