PreQ1 (dihydrochloride)
PreQ1 dihydrochloride is a modified, guanine-derived nucleobase and a precursor of Queuine biosynthesis. preQ1 dihydrochloride binds to the aptamer of PreQ1 riboswitch with high affinity[1].
Product Specifications
CAS Number
86694-45-3
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/preq1-dihydrochloride.html
Purity
98.88
Solubility
DMSO : 125 mg/mL (ultrasonic) |H2O : 14.29 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(NC=C2CN)N=C(N)N1.[H]Cl.[H]Cl
Molecular Formula
C7H11Cl2N5O
Molecular Weight
252.10
Precautions
H302, H315, H319, H335
References & Citations
[1]Connelly CM, et al. Synthetic ligands for PreQ1 riboswitches provide structural and mechanistic insights into targeting RNA tertiary structure. Nat Commun. 2019 Apr 2;10 (1) :1501.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
C2087-29D9 50 µg
CASP7 (Caspase-7, CASP-7, ICE-like Apoptotic Protease 3, ICE-LAP3, Apoptotic Protease Mch-3, CMH-1, Caspase-7 Subunit p20, Caspase-7 Subunit p11, MCH3, CASP7) discontinued
Sign In for Pricing
View Details 
AZQ7SY46-HRP 100 µg/Vial
Anti-Zebrafish ATP6V1A Antibody Picoband® HRP Conjugated
Sign In for Pricing
View Details 
138045-APC 100 µL
IL32 (Interleukin-32, Natural Killer Cells Protein 4, Tumor Necrosis Factor alpha-inducing Factor, IL-32, NK4, TAIF) (APC) discontinued
Sign In for Pricing
View Details