Maresin 1-d5
Product Specifications
Product Name Alternative
CC 122,CC 122 (hydrochloride)
UNSPSC Description
Maresin 1-d5 is the deuterium labeled Maresin 1. Maresin 1, produced by human Mφs from endogenous docosahexaenoic acid (DHA) and a specialized proresolving mediator, stimulates intracellular [Ca2+] and secretion. Maresin 1 possesses anti-inflammatory activity[1][2][3].
Target Antigen
Isotope-Labeled Compounds; Reactive Oxygen Species
Type
Isotope-Labeled Compounds
Related Pathways
Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB;Others
Field of Research
Inflammation/Immunology
Solubility
10 mM in DMSO
Smiles
O[C@H](/C=C\C=C\C=C\[C@@H](C/C=C\CCC(O)=O)O)C/C=C\C/C=C\C([2H])(C([2H])([2H])[2H])[2H]
Molecular Weight
365.52
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. |[2]Markus V Olsen, et al. Maresin 1, a Specialized Proresolving Mediator, Stimulates Intracellular [Ca 2+ ] and Secretion in Conjunctival Goblet Cells. J Cell Physiol. 2020 Jun 8.|[3]Macrophage Proresolving Mediator Maresin 1 Stimulates Tissue Regeneration and Controls Pain|[4]Rodrigo Marcon, et al. Maresin 1, a Proresolving Lipid Mediator Derived From omega-3 Polyunsaturated Fatty Acids, Exerts Protective Actions in Murine Models of Colitis. J Immunol. 2013 Oct 15;191(8):4288-98.
Shipping Conditions
Room temperature
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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