HCAIX-IN-22
HCAIX-IN-22 is a highly selective inhibitor of human carbonic anhydrase (hCA) isoform XII (Ki=9.7 nM) with anticancer activity[1].
Product Specifications
UNSPSC
12352005
Target
Carbonic Anhydrase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/hcaix-in-22.html
Smiles
O=S(C1=CC=C(N/N=C(N(CC)C/2=O)\SC2=C3C(NC4=C/3C=C(Br)C=C4)=O)C=C1)(N)=O
Molecular Formula
C19H16BrN5O4S2
Molecular Weight
522.40
References & Citations
[1]Secci, et al. "New Structural Features of Isatin Dihydrothiazole Hybrids for Selective Carbonic Anhydrase Inhibitors." ACS Medicinal Chemistry Letters (2024) .
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CA XII
Curated Selection
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