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hCAIX-IN-22

Product Specifications

UNSPSC Description

hCAIX-IN-22 is a highly selective inhibitor of human carbonic anhydrase (hCA) isoform XII (Ki=9.7 nM) with anticancer activity[1].

Target Antigen

Carbonic Anhydrase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/hcaix-in-22.html

Smiles

O=S(C1=CC=C(N/N=C(N(CC)C/2=O)\SC2=C3C(NC4=C/3C=C(Br)C=C4)=O)C=C1)(N)=O

Molecular Weight

522.40

References & Citations

[1]Secci, et al. "New Structural Features of Isatin Dihydrothiazole Hybrids for Selective Carbonic Anhydrase Inhibitors." ACS Medicinal Chemistry Letters (2024).

Shipping Conditions

Room temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-159568/hCAIX-IN-22-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-159568/

Clinical Information

No Development Reported

Curated Selection

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