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MED12 Recombinant Rabbit Monoclonal Antibody [PSH06-67]

Mediator of RNA polymerase II transcription, subunit 12 homolog (S. cerevisiae), also known as MED12, is a human gene found on the X chromosome. Mutations in MED12 are responsible for at least two different forms of X-linked dominant mental retardation, Lujan-Fryns syndrome and FG syndrome, as well as instances of prostate cancer. Mutations in MED12 are associated with uterine leiomyomas and breast fibroepithelial tumors (e.g. fibroadenoma and phyllodes tumors).

Product Specifications

CAS Number

9000-83-3

Product Name Alternative

Activator recruited cofactor 240 kDa component antibody Activator-recruited cofactor 240 kDa component antibody ARC240 antibody CAG repeat protein 45 antibody CAGH45 antibody HOPA antibody KIAA0192 antibody MED12 antibody MED12_HUMAN antibody Mediator complex subunit 12 antibody Mediator of RNA polymerase II transcription subunit 12 antibody OPA containing protein antibody OPA-containing protein antibody Thyroid hormone receptor associated protein complex 230 kDa component antibody Thyroid hormone receptor-associated protein complex 230 kDa component antibody TNRC11 antibody Trap230 antibody Trinucleotide repeat containing gene 11 protein antibody Trinucleotide repeat-containing gene 11 protein antibody

Abbreviation

MED12, ARC240, CAGH45, HOPA, KIAA0192, TNRC11, TRAP230

Swiss Prot

Q93074 Human, A2AGH6 Mouse,

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Recombinant protein within human MED12 aa 1,001-1,350.

Isotype

IgG

Clone

PSH06-67

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB

Positive Control

A549 cell lysate, HeLa cell lysate, K-562 cell lysate, LNCaP cell lysate, Jurkat cell lysate, HCT 116 cell lysate, Caco-2 cell lysate, NIH/3T3 cell lysate, C2C12 cell lysate, PC-12 cell lysate, Rat placenta tissue lysate.

Concentration

1 mg/mL

Dilution

WB: 1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 243 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes

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