What is the catalog number for NU-7163?

The catalog number for NU-7163 is HY-116621.

What sizes are available for NU-7163?

NU-7163 is available in the following size(s): 1 Each.

NU-7163 is currently made to order / not held in immediate stock. Contact us for lead time.

Who manufactures NU-7163?

NU-7163 is manufactured by QuantiMol.

What is the estimated delivery time for NU-7163?

Estimated delivery time for NU-7163 is approximately 15 business day(s), depending on your location.

Where can I find the safety data sheet (SDS/MSDS) for NU-7163?

The safety data sheet for NU-7163 is available here: http://file.medchemexpress.com/batch_PDF/HY-116621/.

NU-7163

NU-7163 is an ATP-competitive DNA-PK inhibitor (IC50=0.19 μM; Ki=24 nM) . NU-7163 enhances the cytotoxicity of ionizing radiation against the HeLa human tumor cell line in vitro[1].

Product Specifications

CAS Number

503468-03-9

UNSPSC

12352005

Target

DNA-PK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage; PI3K/Akt/mTOR

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nu-7163.html

Smiles

O=C1C=C(N2CCOC(C2)C)OC3=C1C=CC4=C3C=CC=C4

Molecular Formula

C18H17NO3

Molecular Weight

295.33

References & Citations

[1]Griffin R J, et al. Selective benzopyranone and pyrimido [2, 1-a] isoquinolin-4-one inhibitors of dna-dependent protein kinase: synthesis, structure− activity studies, and radiosensitization of a human tumor cell line in vitro[J]. Journal of medicinal chemistry, 2005, 48 (2) : 569-585.