Glucocorticoid receptor activator 1
Glucocorticoid receptor activator 1 (compound A) is a phenyl aziridine precursor and an activator of the glucocorticoid receptor (GR) . Glucocorticoid receptor activator 1 down-modulates TNF-induced pro-inflammatory gene expression by activating GR and can be utilized in inflammation research[1].
Product Specifications
CAS Number
14593-25-0
UNSPSC
12352005
Hazard Statement
H302-H314
Target
Glucocorticoid Receptor
Type
Reference compound
Related Pathways
Immunology/Inflammation; Vitamin D Related/Nuclear Receptor
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/glucocorticoid-receptor-activator-1.html
Smiles
CNCC(C1=CC=C(OC(C)=O)C=C1)Cl.Cl
Molecular Formula
C11H15Cl2NO2
Molecular Weight
264.15
Precautions
P260-P264-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P363-P405-P501
References & Citations
[1]De Bosscher K, et al. A fully dissociated compound of plant origin for inflammatory gene repression. Proc Natl Acad Sci U S A. 2005 Nov 1;102 (44) :15827-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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